William A. Toscano PhD » Faculty

Research Interests:How environmental agents interacting with human signal transduction systems applies to human health; dioxin; systems biology

Professor, Environmental Health Sciences

Address Division of Environmental Health Sciences 1260 Mayo Building MMC 807 Minneapolis MN 55455 Work Phone: 612-624-2967
Photo of William A. Toscano PhD

Biography:

William Toscano received his Ph.D. in biochemistry from the University of Illinois-Urbana. Previously, he was on the faculty of the Harvard School of Public Health and the Tulane School of Public Health and Tropical Medicine. His research interests include the action of dioxins and other polychlorinated compounds on development, the effects of environmental signals on human reproduction, and the creation of transgenic biosensors of environmental toxicants. His teaching interests include environmental microbiology and environmental, occupational, industrial toxicology, toxico-genomics, and molecular approaches to risk assessment.

  • Ph.D., Biochemistry, The University of Illinois, Urbana-Champaign

Expertise:

Diabetes, Environmental Health, Genetics, Global Health, Risk Assessment, Toxicology, Women’s Health

Professional Experience:

  • Professor of Molecular Toxicology, University of Minnesota School of Public Health, Minneapolis, MN 55455
  • 2000 – 2014 Head Division of Environmental Health Sciences, University of Minnesota School of Public Health, Minneapolis, MN 55455
  • 2000 Present Interim Head, Center for Environmental Health Policy University of Minnesota, Minneapolis, MN 55455
  • 2003 – Present Head, Global Health Initiative, University of Minnesota, School of Public Health, Minneapolis, MN 55455
  • 2003- Present Professor of Molecular Toxicology, Division of Environmental Health Sciences, University of Minnesota School of Public Health, Minneapolis, MN 55455
  • 1999 – Present Professor and Chair, Dept. of Environmental Health Sciences, Tulane University Medical Center School of Public Health & Tropical Medicine, New Orleans, LA 70112
  • 1993 – 1999 Co-director Interdisciplinary Program for Molecular Cell Biology Tulane University. New Orleans, LA 70112
  • 1994- 1999 Associate Professor of Toxicology, Division of Environmental & Occupational Health, University of Minnesota School of Public Health, Minneapolis, MN 55455
  • 1989 – 1993 Associate Professor of Toxicology, Laboratory of Toxicology, Harvard University School of Public Health, Boston, MA 02115
  • 1986 – 1989 Assistant Professor of Toxicology, Laboratory of Toxicology, Harvard University School of Public Health, Boston, MA 02115

Selected Publications:

  • Toscano, W. A., Oehlke, K. P., Kafoury, R. M. [2010] An Environmental Systems Biology Approach to the Study of Asthma, in Pawnkar, R., Holgate, S., and Rosenwasser, L. J. eds. Allergy Frontiers: Future Perspectives, 6: 239-252, Springer.
  • Toscano, W. A., Lee, P., and Oehlke, K. P. [2008] The Role of Environmental Health Research in Understanding Chronic Diseases, Minnesota Medicine 21: 28-29.
  • Toscano, W. A., Mori, C. [2007], Molecular tools for risk assessment, in Robson, M. G., Toscano, W. A., eds, Risk Assessment for Environmental Health, Jossey-Bass, Inc., San Francisco, CA, pp. 155-172.
  • Robson, M. G., Toscano, W. A. eds, [2007] Risk Assessment for Environmental Health, Jossey-Bass, Inc., San Francisco, CA, 628 pp.
  • Kafoury, R. M., Hernandez, J. M., Lasky, J. A., Toscano, W. A., Jr., Friedman, M. [2007] Activation of TRANSCRIPTION FACTOR IL-6 (NF-IL-6) and Nuclear Factor-κB (NF-κB) by Lipid Ozonation Products is Crucial to Interleukin-8 Gene Expression In Human Airway Epithelial Cells, Environ. Toxicol. (In Press)
  • Kandlikar, M., Ramachandran, G., Maynard, A. D., Murdock, B. and Toscano, W. A. [2007] Health risk assessment for nanoparticles: A case for using expert judgment J. Nanoparticle Res. 9: 137-156.
  • Lee, D. H., Lee, I. K,. Song K., Steffes, M., Baker, B., Toscano, W. A., and Jacobs , D. A. Jr [2006] A Strong Dose-Response Relation between Serum Concentrations of Persistent Organic Pollutants and Diabetes: Results from the National Health and Examination Survey 1999-2002 Diabetes Care 29: 1638 – 1644.
  • Toscano, W. A., Oehlke, K, [2005] Systems Biology: New Approaches to Old Environmental Health Problems. Int. J. Environ. Res. Public Health 2: 4-9.
  • Toscano, W., Hovey, C. Hulne, J. Strum, J. Thompson, E. [2004] Children Living in a Perilous Environment. Healthy Generations 4: 6-7. Toscano, W. A., Oehlke, K, [2005] Systems Biology: New Approaches to Old Environmental Health Problems. Int. J. Environ. Res. Public Health 2: 4 – 9.
  • Toscano, W. A., Jr., Toscano, D. G., Toscano, J. S., Gross, M. K. [2003], Molecular Modeling of Manganese Regulation of Calmodulin-dependent Adenylyl Cyclase from Mammalian Sperm. BIOCHEM. BIOPHYS. RES. COMMUNIC. 312: 91-96
  • Coleman, K. P., Toscano, W. A., Jr., Wiese, T. E. [2003] QSAR Models of the in vitro Estrogen Activity of Bisphenol A. QUANT. STRUCT. ACTIVITY RELAT. 22: 78- 87.
  • McLachlan, J. A., Guillette, L. J., Iguchi, T. & Toscano, W. A., Jr. [2001] Environmental Hormones: The Scientific Basis of Endocrine Disruption. NY Academy of Sciences, NY, NY, 142 pp. Book.
  • Mattingly, C. J., and Toscano, W. A., Jr. [2001] Posttranscriptional Silencing of Cytochrome P4501A1 During Zebrafish (Danio rerio)Development. Devel. Dynam. 222: 645-654.
  • Mattingly, C. J., McLachlan, J. A., & Toscano, W. A., Jr. [2001] Green Fluorescent Protein (GFP) as a Marker of Aryl hydrocarbon receptor (AhR) Function in Developing Zebrafish (Danio rerio). ENVIRON. HEALTH PROSPECT. 109:845-849